Abstract #4416
Mapping mean axon diameters using diffusion MRI with oscillating gradients
Junzhong Xu 1 , Hua Li 1 , Kevin D Harkins 1 , Jingping Xie 1 , Mark D Does 1 , and John C Gore 1
1
Institute of Imaging Science, Vanderbilt
University, Nashville, Tennessee, United States
Due to relatively long diffusion times used, small axons
are usually overestimated using PGSE-based models. In
the current study, the OGSE method was implemented in
fixed spinal cord measurements with much shorter
effective diffusion times to enhance detection
sensitivity to small axons. The results show that the
fitted mean axon diameters are in very good agreement
with histology.
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