Abstract #4217
Comparing the microvascular specificity of the 3 T and 7 T BOLD response
Simon Daniel Robinson 1 , Florian Fischmeister 1,2 , Gnther Grabner 1 , Moritz Wurnig 1,2 , Jakob Rath 1,2 , Thomas Foki 1,2 , Eva Matt 1,2 , Siegfried Trattnig 1 , Roland Beisteiner 1,2 , and Alexander Geissler 1,2
1
Department of Biomedical Imaging and
Image-guided Therapy, Medical University of Vienna,
Vienna, Vienna, Austria,
2
Department
of Neurology, Medical University of Vienna, Vienna,
Austria
The specificity of the BOLD response to microvascular
rather than draining vein signal is understood to
increase with field strength. This understanding is
based on image SNR and relaxation rates, however. In the
light of recent studies showing less than linear
increases of time-series SNR and activation statistics
with field strength we re-examined the specificity of
the BOLD response in high resolution fMRI at 3T and 7T
with 12 subjects who performed a hand task. fMRI data
were analysed with ICA and compared with 7T SWI. There
was a significant increase in sensitivity but not
specificity with field strength.
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