Abstract #4116
Water Unsuppressed 1H MR Spectroscopic Imaging Of The Prostate
Nassim Tayari 1 , Arend Heerschap 1 , and Alan J. Wright 1
1
Dept. of Radiology, RadboudUMC, Nijmegen,
Gelderland, Netherlands
Proton MR spectroscopic imaging is commonly performed
with water signal suppression to avoid artifacts from
side bands of the large water signal, but this signal
can be very useful for estimating metabolite
concentrations by providing a line-shape reference and a
quantification of the water signal. In this study we
developed water unsuppressed 3D MRSI of the prostate and
used it to provide choline concentration maps for
localization of prostate cancer. We observed that high
choline concentrations co-localised to tumour foci as
confirmed on histopathological staining of radical
prostatectomy specimens.
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