Abstract #4071
Simulation of Optical Breast Density Measurements Using Structured Light Illumination in A Patient-Specific Anatomical Breast Model Built from 3D MRI-Segmented Breast Density
Jessica Kwong 1 , Farouk Nouizi 1 , Yifan Li 1 , Gultekin Gulsen 1 , and Min-Ying Lydia Su 1
1
Tu & Yuen Center for Functional
Onco-Imaging, Department of Radiological Sciences,
University of California, Irvine, CA, United States
Diffuse Optical Imaging can potentially be used to
measure quantitative breast density. We used MRI-based
density segmented from healthy breasts to reconstruct a
3D model of the breast and the dense tissue for optical
imaging simulation. Near infrared lights of various
patterns were illuminated to the breast from one side
and received from the other side. The light propagation
through the 3D tissue model was simulated and
reconstructed to generate the 3D absorption maps. The
percentage of the high-absorbing dense tissue from the
optical reconstructions is highly correlated with the
true percent density measured by MRI, with r= 0.9866.
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