Abstract #4059
Intravoxel Incoherent Motion MRI for Tumor Subtype Differentiation in Locally Advanced Breast Cancer
Gene Young Cho 1,2 , Linda Moy 1,3 , Sungheon Kim 1 , Ana Paula Klautau Leite 4 , Steven Baete 1 , Jim Babb 1 , Daniel K Sodickson 1 , and Eric E Sigmund 1
1
Radiology - Bernard and Irene Schwartz
Center for Biomedical Imaging, New York University
School of Medicine, New York, Select, United States,
2
Sackler
Institute of Graduate Biomedical Sciences, New York
University, New York, NY, United States,
3
Radiology,
New York University Cancer Institute, New York, NY,
United States,
4
Radiology,
Hospital das Clnicas, School of Medicine, University of
So Paulo, So Paulo, SP, Brazil
An accurate, simple method using imaging to determine
cancer type has long been a goal in oncology.
Determination of tumor subtypes through imaging can be
advantageous in the strategic planning of therapy and
limit the need for invasive biopsy procedures. In MRI,
intravoxel incoherent motion (IVIM) can play an
important role as it is most commonly employed due to
its sensitivity to tumor cell density and vascularity,
both components of aggressiveness. In this study, highly
sampled DWI data is used to perform IVIM analysis in a
cohort of breast cancer patients in a 3T clinical
scanner.
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