Abstract #4013
Whole-body Dixon for skeletal muscle fat fraction quantification in neuromuscular disorders
Benjamin Marty 1 , Pierre-Yves Baudin 1 , Benjamin Robert 2 , Alexey Shukelovich 1 , Robert-Yves Carlier 3 , Noura Azzabou 1 , and Pierre G Carlier 1
1
AIM-CEA Institut de Myologie, Laboratoire
RMN, Paris, France,
2
Siemens
Healthcare, Saint-Denis, France,
3
AP-HP
Hpital Universitaire Raymond-Poincar, Garches, France
Fatty infiltration of muscles is a marker of disease
progression in muscular dystrophies. Although routine
T1-weighted imaging gives an indication of the presence
or absence of muscular fat infiltration, it is difficult
to extract quantitative data from these images. On the
contrary, Dixon methods can give quantitative measures
of water and fat fractions. Generally, whole-body exams
consist in the acquisition of a T1w sequence, followed
by Dixon acquisitions on targeted regions to
quantitatively assess fat infiltration. In our study we
demonstrate that the use of a well calibrated sequence
allows replacing whole-body T1w imaging by a whole-body
Dixon imaging.
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