Abstract #3944
Synthetic LGE Derived from Cardiac T1 Mapping for Simultaneous Assessment of Focal and Diffuse Cardiac Fibrosis
Kyungpyo Hong 1,2 , Edward VR. DiBella 1 , Eugene G. Kholmovski 1 , Ravi Ranjan 3 , Christopher J. McGann 3 , and Daniel Kim 1
1
UCAIR, Department of Radiology, University
of Utah, Salt Lake City, Utah, United States,
2
Department
of Bioengineering, University of Utah, Salt Lake City,
Utah, United States,
3
CARMA,
Department of Internal Medicine, University of Utah,
Salt Lake City, Utah, United States
While late-gadolinium-enhanced (LGE) MRI is the gold
standard for detection of focal myocardial scarring, it
is less effective than cardiac T1 mapping for assessment
of diffuse fibrosis. We sought to derive synthetic LGE
images from saturation-recovery based cardiac T1 maps
for simultaneous assessment of focal and diffuse cardiac
fibrosis. In 21 short-axis planes with different
myocardial lesions created by RF ablation, standard and
synthetic LGE images showed similar image quality and
signal contrast ratio of the lesion-myocardium and
blood-myocardium pairs. The new approach provides a
means to simultaneously assess focal and diffuse cardiac
fibrosis using cardiac T1 mapping alone.
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