Abstract #3827
Comparison of standardized uptake values in normal structures and breast cancer metastases using PET/CT and PET/MRI
Akshat C Pujara 1 , Carolyn Wassong 1 , Roy A Raad 1 , James Babb 1 , Linda Moy 1 , and Amy Melsaether 1
1
New York University School of Medicine, New
York, NY, United States
Validation of MR attenuation correction (MRAC) is
required for comparison of SUVs derived from PET/CT with
those derived from PET/MRI. The current study
demonstrates that SUVmax generated from MRAC correlates
well with SUVmax generated from PET/CT for normal
structures and breast cancer metastases, and can thus be
used for quantification of FDG activity. Interestingly,
the metabolic activity of breast cancer metastases
during the interval between PET/CT and PET/MRI differed
depending on the site of spread. Further investigation
is needed to evaluate the potential role of SUV
measurements in tailoring imaging protocols to the
metabolic activity of organ-specific metastases.
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