Abstract #3625
The effect of cardiac phase on liver diffusion tensor imaging (DTI)
Oi Lei Wong 1,2 , Glady G Lo 3 , Raymond Lee 3 , Po Lung Polo Chan 3 , Wing Wa Li 3 , Siu Ki Yu 4 , and Michael D Noseworthy 5,6
1
Department of Medical Physics and Applied
Radiation Science, McMaster University, Hamilton,
Ontario, Canada,
2
Medical
Physics and Research Department, Hong Kong Sanatorium &
Hospital, Hong Kong, Hong Kong, Hong Kong,
3
Department
of Diagnostic & Interventional Radiology, Hong Kong
Sanatorium & Hospital, Hong Kong, Hong Kong,
4
Medical
Physics and Research Department, Hong Kong Sanatorium &
Hospital, Hong Kong, Hong Kong,
5
Department of
Electrical and Computer Engineering, McMaster
University, Hamilton, Ontario, Canada,
6
St.Joseph's
Healthcare, Hamilton, Ontario, Canada
Performing diffusion weighted imaging at the left liver
lobe is often problematic due to regional signal loss.
From the literature, the regional signal loss is
possibly related to respiratory and cardiac motion. In
this study, we studied the effect of cardiac phase, and
hence motion, on liver DTI metrics, performed at various
cardiac trigger delay settings. Significant change in DT
metrics between systole and diastole was observed in the
left liver lobe, but not the right liver lobe. This
suggests that these metrics are sensitive to cardiac
phase, and thus likely deformation.
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