Abstract #3568
3D dynamic contrast-enhanced (DCE) MR renography; Evaluation of image quality and estimation of GFR comparing Kwic and Flash sequences
Eli Eikefjord 1,2 , Erling Andersen 3 , Jan Anker Monssen 4 , Erlend Hodneland 5 , Frank Zoellner 6 , Erik Hanson 7 , Arvid Lundervold 5,8 , and Jarle Tor Rrvik 4,9
1
Haukeland University Hospital (HUH), Bergen,
Hordaland, Norway,
2
University
of Bergen (UoB), Bergen, Hordaland, Norway,
3
Dept.
of Clinical Engineering, HUH, Bergen, Norway,
4
Dept.
of Radiology, HUH, Bergen, Norway,
5
Dept.
of Biomedicine, UoB, Bergen, Norway,
6
Dept.
of Computer Assisted Clinical Medicine, Heidelberg
University, Mannheim, Germany,
7
Dept.
of Mathematics, UoB, Bergen, Norway,
8
HUS,
Bergen, Norway,
9
Dept.
of Clinical Medicine, UoB, Bergen, Norway
A reliable and reproducible MR Renography technique may
provide valuable information about renal functional
status. In this project we studied the relationship
between image quality and the ability to estimate GFR
reliably, using two different DCE-MRI sequences (Kwic
and Flash) in 10 healthy subjects and the same
post-processing scheme. The correlation between image
quality and accuracy appeared to be strong. Considering
the Iohexol-clearance as GFR gold-standard, we found the
FLASH sequence to give better GFR-estimates than KWIC.
In quantitative MRI image quality should be documented
to assure good technical compromises in the design of
fast imaging techniques.
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