Abstract #3517
Diffusion Tensor Imaging for White Matter Alterations in Chronic Cocaine Dependents
Wang Zhan 1 , Hong Gu 2 , and Yihong Yang 2
1
University of Maryland, College Park, MD,
United States,
2
National
Institute on Drug Abuse, MD, United States
Neuronal dysfunctions associated with cocaine additions
have been wildly reported inside and outside the
dopaminergic reward system, yet the structural basis for
the abnormal circuitry responses is still unclear. A
diffusion tensor imaging (DTI) study was performed using
relatively larger group size and more comprehensive
subject characterizations to investigate the white
matter (WM) alteration patterns in chronic cocaine
users. Our data show a complex DTI alteration pattern
across multiple regions inside and outside the
dopaminergic system.
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