Abstract #3422
Regional analysis of DTI-FA in Milder TBI
Ramtilak Gattu 1 , Randall R Benson 2,3 , Zhifeng Kou 4 , Gabriela Trifan 3 , and Ewart Mark Haacke 4,5
1
Radiology, Wayne State University, Detroit,
MI, United States,
2
Neurology
and Radiology, Center for Neurologic Studies, Detroit,
MI, United States,
3
Center for Neurologic
Studies, NOVI, MI, United States,
4
Biomedical
Engineering & Radiology, Wayne State University,
Detroit, MI, United States,
5
The
MRI Institute for Biomedical Research, Detroit, MI,
United States
27 White matter brain regions were analyzed using a
semi-automated regional approach, using the DTI scalar
measures, Fractional Anisotropy (FA) for controls and
traumatic brain injury groups, to identify the threshold
for which these regions will show decreased FA. FA maps
were created from diffusion images for eighty seven
controls and one hundred and eighty TBI patients that
underwent trauma imaging scanning protocol. TBI
population showed a negative shift in the resulting FA
histograms. These regions with decreased FA can be used
to differentiate between normal controls and TBI
subjects.
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