Abstract #3311
A Repeatability Study of Amide Proton Transfer Imaging in the Head and Neck at 3T
Shuzhong Chen 1 , Wang Lam 1 , Ann D King 1 , Kunwar S Bhatia 1 , Benjamin King Hong Law 1 , Qinwei Zhang 1 , David Ka Wai Yeung 1 , Yi-Xiang J Wang 1 , Jinyuan Zhou 2 , and Jing Yuan 1,3
1
Imaging and Interventional Radiology, The
Chinese University of Hong Kong, Shatin, NT, Hong Kong,
2
Department
of Radiology, Johns Hopkins University School of
Medicine, Baltimore, Maryland, United States,
3
CUHK
Shenzhen Research Institute, Shenzhen, Guangdong, China
Our pilot study has showed that APT-MRI is feasible for
the use in the head and neck (HN) and has potentials for
HN cancer characterization at 3T. However, HN-APT-MRI is
technically challenging due to tissue heterogeneity,
pronounced susceptibility and various motions, which may
potentially compromise the APT quantification in
different scans. To this end, we investigated the
repeatability of HN-APT-MRI on healthy volunteers and
successfully demonstrated that consistent inter-scan APT
contrast could be achieved in major HN tissues. This
study is helpful to establish the HN-APT-MRI
repeatability so as to ensure its reliability for future
clinical use.
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