Abstract #3294
Using Simultaneous Multi-Slice Excitation to Accelerate CEST Imaging
Dapeng Liu 1,2 , Rong Xue 1,2 , Jinyuan Zhou 3,4 , Jing An 5 , Xinyuan Miao 1 , and Danny JJ Wang 2,6
1
State Key Laboratory of Brain and Cognitive
Science, Beijing MRI Center for Brain Research,
Institute of Biophysics, Chinese Academy of Sciences,
Beijing, China,
2
UCLA-Beijing
Joint Center for Advanced Brain Imaging, Beijing, China
and Los Angeles, California, United States,
3
Department
of Radiology, Johns Hopkins University, Baltimore, MD,
United States,
4
F.M.
Kirby Research Center for Functional Brain Imaging,
Kennedy Krieger Institute, Baltimore, MD, United States,
5
Siemens
Shenzhen Magnetic Resonance Ltd, Shenzhen, China,
6
Department
of Neurology, University of California Los Angeles, Los
Angeles, United States
Chemical exchange saturation transfer (CEST) imaging is
a novel MRI technique that can detect low-concentration
solutes in tissue compared to routine water MR images.
However, a long scan time due to multiple repetitions
required to acquire a full frequency spectrum or to
increase signal-to-noise ratios and a long saturation
pulse (or pulse train) have restricted its practical
clinical application that typically needs multi-slice
measurements. Here we present an efficient and
accelerated CEST imaging technique using a simultaneous
multi-slice (SMS) excitation Turbo-FLASH (TFL) sequence
in human brain at 3 T.
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