Abstract #3169
Accelerated In Vivo 3D Chemical Exchange Saturation Transfer (CEST) Imaging using dynamic Compressed Sensing
Juyoung Lee 1 , Paul Kyu Han 1 , Seung-Hong Choi 2 , Sung-Hong Park 1 , and Jong Chul Ye 1
1
Department of Bio and Brain Engineering,
KAIST, Daejeon, Yuseong-gu, Korea,
2
Department
of Radiology, Seoul National University Hospital, Seoul,
Korea
CEST can be combined with 3D gradient echo imaging to
minimize distortion and avoid slice-dependent saturation
frequency variations, but the spatial coverage may be
limited. One potential approach to overcome this
limitation is to use compressed sensing (CS). In this
study, we successfully obtained in vivo 3D CEST images
using k-t FOCUSS at 3T. Experimental results show that
CS acceleration by a factor of 4 works well for both 3D
CEST-bSSFP and 3D CEST-FISP and improves the z-spectrum
compared to parallel imaging method, which confirms that
combination of CS may be a good solution for 3D- CEST
imaging.
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