Abstract #3078
Mapping the Resting State Functional Connectivity in the GPR88 KO mouse brain
Tanzil Mahmud Arefin 1,2 , Anna Mechling 2,3 , Sami Ben Hamida 4 , Hsu-Lei Lee 2 , Dominik V. Elverfeldt 2 , Jrgen Hennig 2 , Brigitte Kieffer 4 , and Laura-Adela Harsan 2
1
Computational Neuroscience, Bernstein Center
Freiburg, Freiburg, Baden-Wrttemberg, Germany,
2
Medical
Physics, University Medical Center Freiburg, Freiburg,
Baden-Wrttemberg, Germany,
3
Department
of Biology, University of Freiburg, Freiburg,
Baden-Wrttemberg, Germany,
4
IGBMC,
Illkirch, Alsace, France
Functional communication between brain regions plays a
key role in complex cognitive process. Emerging studies
show that rsfMRI can reveal the modifications in
functional brain connectivity due to psychiatric
disorders or drug effects. This study was aimed to
scrutinize the functional connectivity modifications in
GPR88 Knock Out (KO) mice using rsfMRI technique, which
has not been examined yet and might be interesting in
the perspective of neurological or psychiatric disorders
and drug research.
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