Abstract #3069
Estimating the Physiological Response Functions in Resting-State BOLD: The Effect of Acquisition Speed
Ali M Golestani 1,2 and J Jean Chen 1,2
1
Rotman Research Institute, Baycrest,
Toronto, ON, Canada,
2
University
of Toronto, Toronto, ON, Canada
Physiological signals have an effect on resting state
BOLD, that typically described by transfer functions,
estimated from datasets with typically repetition times
of 2 s, preventing accurate sampling of all signal
components. In this study we assess whether such
limitations affect the estimation of the BOLD
hemodynamic response function to physiological signals
by using typical (TR = 2 s) and high temporal resolution
(TR < 400 ms) data. We found that data acquired at
typical temporal resolution produced transfer functions
that are similar to those based on high temporal
resolution data, suggesting the estimation to be
insensitive to sampling rate.
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