Abstract #3045
Bilateral Auditory Cortex Ablation Alters the Tonotopic Organizaiton of the Inferior Colliculus
Jevin W. Zhang 1,2 , Shu-juan Fan 1,2 , Patrick P. Gao 1,2 , Joe S. Cheng 1,2 , Dan H. Sanes 3 , and Ed X. Wu 1,2
1
Laboratory of Biomedical Imaging and Signal
Processing, the University of Hong Kong, Hong Kong, Hong
Kong, China,
2
Department
of Electrical and Electronic Engineering, the University
of Hong Kong, Hong Kong SAR, China,
3
Center
for Neural Science, New York University, New York, New
York, United States
bSSFP fMRI with swept source imaging paradigm was
applied on the experimental and age-matched control
group to examine the effect of bilateral auditory cortex
ablation on the tonotopic organization in inferior
colliculus (IC). The differences between the changes of
encoded frequency along the tonotopic axis suggested the
tuning curve bandwidth center was shifted toward
different directions for neurons at different portions
of the IC. This study clearly demonstrated that cortical
input can modulate the tonotopic organization in IC.
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