Abstract #2995
Complex interactions of physiological noise and acceleration on tSNR in 3D EPI
Nadine N Graedel 1 , Mark Chiew 1 , Stuart Clare 1 , and Karla L Miller 1
1
FMRIB Center, University of Oxford, Oxford,
Oxfordshire, United Kingdom
3D EPI provides a number of advantages over 2D
multi-slice acquisition for high-resolution fMRI.
However, the temporal signal characteristics of 3D
sampling have not been fully characterized, particularly
with respect to the interaction of physiological noise
and acceleration. In this work we looked at the effect
of varying slice acceleration factors on temporal SNR at
different resolutions for in vivo and phantom
acquisitions. We found a significantly different
behavior of the in vivo tSNR compared to predictions
based on thermal noise considerations alone. We present
an investigation into potential sources of these
effects.
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