Abstract #2982
Simulation of BOLD Sensitivity of Single-Shot Multi-Echo EPI versus Sample-Induced Susceptibility Gradients
Brice Fernandez 1 and Michael Czisch 2
1
Applications and Workflows Europe, GE
Healthcare, Munich, Germany,
2
Neuroimaging
Research Group, Max Planck Institute of Psychiatry,
Munich, Germany
For functional MRI, the use of a single-shot multi-echo
EPI (MEPI) has been shown to be an advantageous
acquisition scheme. Among others factors, MEPI increases
fMRI BOLD sensitivity and offers increased robustness to
sample-induced susceptibility gradients. In addition,
parallel imaging has been shown to significantly reduce
EPI distortions but suffers from SNR loss. However, the
limit of BOLD sensitivity as a function of the
susceptibility gradients is unknown. Here, we
investigate the BOLD sensitivity as a function of the
susceptibility gradients using simulations and
considering a MEPI acquisition protocol with a high
acceleration factor, and an echo combination method.
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