Abstract #2908
Constrained Source Space Spectroscopy: Multivoxel Spectroscopy Without a Gradient Readout
Karl Landheer 1 , Sunit Das 2 , and Simon Graham 1
1
Medical Biophysics, University of Toronto,
Toronto, Ontario, Canada,
2
St.
Michael's Hospital, Toronto, Canada
A novel technique was developed that can measure the
spectra of discrete voxels simultaneously, without the
need for a gradient readout. The technique utilizes a
modified PRESS sequence to excite multiple voxels,
measures their spectra simultaneously using multichannel
receiver coils, and reconstructs the individual voxel
spectra using SENSE. Good agreement was demonstrated in
vivo using both qualitative and quantitative
measurements of the techniques efficacy when compared
to single voxel spectroscopy, in healthy adults and in a
patient with low-grade glioma.
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