Abstract #2902
Manipulator-mounted optical/NMR dual-modality probe for multimodality scanning in MR guided and robot-assisted interventions
Junmo An 1 , Ahmet E. Sonmez 1 , Mahmut Unan 1 , Robert D. Darrow 2 , Ileana Hancu 2 , R. Jason Stafford 3 , Andrew G. Webb 4 , and Nikolaos V. Tsekos 1
1
University of Houston, Houston, Texas,
United States,
2
GE
Global Research Center, New York, United States,
3
University
of Texas MD Anderson Cancer Center, Texas, United
States,
4
Leiden
University, Leiden, Netherlands
The aim of this work is to implement a dual modality
optical/NMR probe for intraoperative loco-regional and
spatially co-registered collection on light-induced
fluorescence and NMR spectra. The multi-fiber optical
sensor that functions as an emitter and receiver is
surrounded by a solenoid microcoil for 1H spectroscopy
or MR imaging. The probe is mounted on an MR compatible
manipulator for intraoperative biosensing in situ and
mechanical scanning to map the spatial distribution of
optical/NMR signal sources. Testing was conducted on a
multi-compartment phantom of fluorophores and
metabolites demonstrated the MR compatibility of the
device and the spatial matching of the distribution of
optical and MR signal sources.
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