Abstract #2866
Magnetic Nanoparticles extracted from magnetotactic bacteria as contrast agents for MRI
Pasquina Marzola 1 , Leonardo Ghin 2 , Stefano Tambalo 3 , Giamaica Conti 3 , Silvia Mannucci 3 , Alice Busato 3 , Elvira Fantechi 4 , Claudia Innocenti 4 , Claudio Sangregorio 4 , Alessandro Lascialfari 5 , Tomas Orlando 5 , Roberto Bassi 2 , and Andrea Sbarbati 3
1
Department of Computer Science, University
of Verona, Verona, Italy,
2
Department
of Biotechnology, University of Verona, Verona, Italy,
3
Department
of Neurological and Movement Science, University of
Verona, Verona, Italy,
4
INSTM-LaMM,
Dept. of Chemistry, University of Florence, Florence,
Italy,
5
Department
of Physics, University of Milan, Milan, Italy
Naturally occurring iron-oxide nanoparticles, namely
Magnetosomes (MS), are here proposed as theranostic
agents for imaging and thermotherapy of tumors.
Magnetosomes, produced by magnetotactic bacteria, are
organized in chains that are used by bacteria as a
compass for geomagnetic navigation. In this paper ,
several techniques have been used to characterize
magnetic nanoparticles and we demonstrate that MS
extracted from Magnetospirillum gryphiswaldence strain
MSR-1 have high transversal relaxivity and high
hyperthermal efficiency.
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