Abstract #2745
Effect of k-Space Weighted Image Contrast with golden-angle view ordering on diagnostic accuracy for lesion discrimination
Melanie Freed 1 and Sungheon Kim 1
1
Center for Biomedical Imaging, Department of
Radiology, NYU School of Medicine, New York, NY, United
States
In this study, we quantitatively evaluate temporal
blurring of DCE-MRI data sets generated using a k-space
weighted image contrast image sharing technique with
golden-angle view ordering (GA-KWIC) by examining the
effect on estimated pharmacokinetic model parameters in
simulation. Estimated Ktrans values have a larger bias
for smaller lesions and higher true Ktrans values,
resulting in errors in estimated diagnostic accuracy for
discrimination of benign and malignant lesions. However,
the errors incurred are small compared to other sources
of error in clinical studies. Therefore, GA-KWIC can be
used to improve temporal resolution of DCE-MRI data
without negatively impacting diagnostic accuracy
estimation.
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