Abstract #2669
Lateralisation of the connections between Broca's area and the pre-SMA in relation to handedness
Henrietta Howells 1 , Flavio Dell'Acqua 2,3 , Anoushka Leslie 2 , Michel Thiebaut de Schotten 1,4 , Mitul Mehta 2 , Declan G. Murphy 1 , Andrew Simmons 2 , and Marco Catani 1
1
Forensic and Neurodevelopmental Sciences,
Institute of Psychiatry, London, United Kingdom,
2
Department
of Neuroimaging, Institute of Psychiatry, London, United
Kingdom,
3
NIHR Biomedical Research Centre for
Mental Health at SLAM NHS Foundation Trust, Institute of
Psychiatry, London, United Kingdom,
4
Universit
Pierre et Marie Curie-Paris 6, Centre de Recherche de
l'Institut du Cerveau et de la Moelle pinire, Paris,
France
The frontal aslant tract (FAT) is a newly described
pathway connecting posterior Broca's territory with the
pre-SMA and cingulate cortex. This tract is
significantly left-lateralised in right-handed subjects
and plays a role in speech initiation. It has not yet
been studied in left-handers. We used spherical
deconvolution diffusion tractography to compare this
tract in right and left-handed subjects, finding
left-lateralisation was not significant in the
left-handed group. This may be reflective of more
heterogeneous patterns of functional activation for
language in left-handed individuals.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
