Abstract #2569
Motion and eddy-current correction in high b-value diffusion MRI: Systematic registration errors and how to avoid them
Markus Nilsson 1 , Filip Szczepankiewicz 2 , Danielle van Westen 3 , and Oskar Hansson 4
1
Lund University Bioimaging Center, Lund
University, Lund, Sweden,
2
Dept.
of Medical Radiation Physics, Lund University, Sweden,
3
Dept.
of Diagnostic Radiology, Lund University, Sweden,
4
Clinical
Memory Research Unit, Dept. of Clinical Sciences Malm,
Lund University, Sweden
Motion correction of high b-value diffusion MRI data can
be performed using the non-diffusion weighted image as
reference, but here we show that this conventional
motion correction leads to substantial registration
errors in terms of misalignment between low and high
b-value volumes. We suggest a method that can eliminate
this registration error by extrapolating reference
volumes from low b-value data to high b-value data. The
improved motion correction leads to a reduction in the
standard deviation in the FA of up to 40%, which is
associated to a large increase in the statistical power
of group studies.
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