Abstract #2533
Quantification of Aortic Stiffness across the Cardiac Cycle Using Magnetic Resonance Elastography: Reproducibility Study
Anirudh Damughatla 1 , William Kenyhercz 2 , Brian Raterman 2 , Peter Wassenaar 2 , Richard White 1,3 , and Arunark Kolipaka 1,3
1
Biomedical Engineering, The Ohio State
University, Columbus, Ohio, United States,
2
Radiology,
The Ohio State University Wexner Medical Center,
Columbus, Ohio, United States,
3
Radiology
and Internal Medicine, Division of Cardiology, The Ohio
State University Wexner Medical Center, Columbus, Ohio,
United States
Arterial stiffness is an important indicator for
diagnosing many cardiovascular diseases. It has been
shown that arterial stiffness varies across the cardiac
cycle and has different effects in disease progression
during systole when compared to diastole. In-vivo aortic
magnetic resonance elastography (MRE) was performed in a
3T-MRI scanner on 4 volunteers aged between 20-33 years
to determine the stiffness of the aorta across the
cardiac cycle. Initial results demonstrate the
feasibility and reproducibility of the MRE-derived
stiffness and also suggest higher stiffness values at
end-systole compared to end-diastole.
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