Abstract #2425
Instantaneous Signal Loss simulation (InSiL) An improved algorithm for myocardial T1 mapping using the MOLLI sequence
Jiaxin Shao 1 , Yutaka Natsuaki 2 , Bruce Spottiswoode 2 , Kim-Lien Nguyen 1,3 , and Peng Hu 1,4
1
Department of Radiological Sciences, David
Geffen School of Medicine, University of California, Los
Angeles, CA, United States,
2
Siemens
Healthcare USA, Inc., IL, United States,
3
Division
of Cardiology, David Geffen School of Medicine,
University of California, Los Angeles, CA, United
States,
4
Biomedical
Physics Inter-Departmental Graduate Program, University
of California, Los Angeles, CA, United States
We propose a new T1 mapping method, Instantaneous Signal
Loss simulation (InSiL), for the MOLLI sequence. InSiL
was evaluated against standard MOLLI using phantom
study, and in 10 healthy volunteers at 1.5T. Phantom
results show that the maximum absolute error by InSiL is
less than 12ms, while that by MOLLI is more than 300ms
for T1 values around 223ms-1641ms. InSiL reduced MOLLI
T1 absolute error from 197ms to 4ms on average for
T1>1000ms, HR≥80bpm. The native myocardial T1 values by
InSiL were greater than that by MOLLI by 238.09.0ms
(1166.023.1ms vs. 928.121.8ms) at an average heart
rate of 63.711.2bpm.
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