Abstract #2376
Comparison of distributed parameter and Fermi modelling of cardiac MR perfusion with CT perfusion in coronary artery disease versus invasive coronary angiography
Giorgos Papanastasiou 1,2 , Michelle Williams 2 , Mark Dweck 2 , Saeed Mirsadraee 1 , Nick Weir 3 , Shirjel Alam 2 , Colin Stirrat 2 , David Newby 1,2 , and Scott Semple 1,2
1
Clinical Research Imaging Center, University
of Edinburgh, Edinburgh, Lothian, United Kingdom,
2
Centre
for Cardiovascular Science, University of Edinburgh,
Edinburgh, Lothian, United Kingdom,
3
NHS
Medical Physics, University of Edinburgh, Edinburgh,
Lothian, United Kingdom
My PhD focuses in modeling and quantification of
myocardial blood flow (MBF) using dynamic contrast
enhanced magnetic resonance (DCE-MRI) which can
potentially be used for the diagnosis and prognosis of
coronary artery disease and also the assessment and/or
planning of therapy and intervention. Furthermore, I
work in a multimodality cross-validation study of MBF
using DCE-MRI, computed tomography perfusion and
positron emission tomography perfusion in patients with
coronary artery disease. Clinically, we aim to overcome
critical limitations of individual techniques and use
the merits of each technique to gain a better
understanding of MBF at the clinical setting.
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