Abstract #2342
Real-time tracking of temperature, T1 and T2* during the onset of thermal damage in ex vivo and in vivo rabbit thigh muscle
Nick Todd 1 , Allison Payne 2 , and Dennis L Parker 2
1
Wellcome Trust Centre for Neuroimaging,
London, United Kingdom,
2
Radiology,
UCAIR, Salt Lake City, UT, United States
A hybrid PRF/T1/T2* sequence is used to measure tissue
temperature and the relaxation parameters T1 and T2* in
real time during MR-guided focused ultrasound (MRgFUS)
heating of in vivo and ex vivo rabbit thigh muscle. T1
and T2* are analyzed as functions of temperature and
thermal dose to investigate whether they are sensitive
to the various processes that occur during the onset and
progression of tissue thermal damage.
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