Abstract #2153
The repeatability of the Magnetic Resonance Elastography derived stiffness value in the liver
Alexander D Cohen 1 , Mark D Hohenwalter 2 , and Kathleen M Schmainda 1,2
1
Biophysics, Medical College of Wisconsin,
Milwaukee, WI, United States,
2
Radiology,
Medical College of Wisconsin, Milwaukee, WI, United
States
Magnetic Resonance Elastography (MRE) has gained
prominence for its ability to stage liver fibrosis. MRE
measures the propagation of acoustic shear waves,
generated by a passive driver, through liver tissue. MRE
gives estimates of liver stiffness, which have directly
correlated with fibrosis grade in preliminary studies.
MRE repeatability was assessed in a cohort of normal
volunteers and cirrhotic patients imaged twice in one
scanning session. Repeatability was excellent for both
the volunteers and cirrhotic patients, and indicate
changes must be larger than ~10% to be significant for
longitudinal studies and ~10-30% to be significant for
between group studies.
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