Abstract #2149
The value of severe liver iron overload to predict cardiac iron level
Xiaodong Chen 1,2 , Hui Zhang 3 , Xihai Zhao 3 , Huailing Zhang 4 , Biling Liang 5 , and Hua Guo 3
1
Sun Yat-Sen Memorial Hospital, Guangzhou,
Guangdong, China,
2
Guangdong
Medical College, Guangdong, China,
3
Biomedical
Engineering&Center for Biomedical Imaging
research,School of Medicine,Tsinghua University,
Beijing, China,
4
School
of Information Engineering, Guangdong Medical College,
Guangdong, China,
5
Sun
Yat-Sen Memorial Hospital, Guangdong, China
Cardiac failure is the main causes of death in patients
with thalassemia major 1,2. But its diagnosis is often
hysteretic in clinical practice, which probably in
consequence of the unpredictability of cardiac iron
deposition as well as the lag of appearance of symptoms,
Thus, it is vital to monitor the cardiac iron level even
in asymptomatic patients. Hepatic iron concentration has
been widely used as the indicator of this disease.
However, it lacks extensive investigation about the
relationship between hepatic iron overload and
myocardium iron overload, especially when the liver has
severe deposition.
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