Abstract #1832
Changes of brain activities and metabolites in the right dorsolateral prefrontal cortex in patients with obsessive compulsive disorder
Shin-Eui Park 1 and Gwang-Woo Jeong 1,2
1
Chonnam National University,
Interdisciplinary Program of Biomedical Engineering,
Gwangju, Chonnam, Korea,
2
Chonnam
National University Hospital, Chonnam National
University, Department of Radiology, Medical School,
Gwangju, Korea
The obsessive compulsive symptoms are mainly related to
the dysfunctional cortico-striatal-thalamic circuit (CSTC),
a network involving the prefrontal cortex, striatum,
thalamus in pathogenesis. Several neuroimaging or
spectroscopy studies revealed differential brain
activation patterns during performing memory tasks and
metabolic concentration changes in the CSTC circuits.
However, the findings from the studies mentioned above
have not been consistent. We performed 1H MRS and fMRI
study during the implicit memory tasks for the
quantification of the brain metabolites and
identification of the brain activation patterns in OCD
patients.
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