Abstract #1817
Differential involvement of cortical and cerebellar areas using dominant and non dominant hands
Adnan Alahmadi 1,2 , Rebecca Samson 1 , David Gasston 3 , Egidio D'Angelo 4,5 , Ahmed Toosy 1,6 , and Claudia A.M. Wheeler-Kingshott 1
1
NMR Research Unit, Department of
Neuroinflammation, Queen Square MS Centre, UCL Institute
of Neurology, London, United Kingdom,
2
Department
of Diagnostic Radiology, Faculty of Applied Medical
Science, KAU, Jeddah, Saudi Arabia,
3
Department
of Neuroimaging, Institute of Psychiatry, King's College
London, London, United Kingdom,
4
Department
of Brain and Behavioral Sciences, Neurophysiology Unit,
University of Pavia, Pavia, Italy,
5
Brain
Connectivity Center, IRCCS C.Mondino, Pavia, Italy,
6
NMR
Research Unit, Department of Brain Repair and
Rehabilitation, Queen Square MS Centre, UCL Institute of
Neurology, London, United Kingdom
We investigated common and specific brain activations in
contra and ipsi-lateral (CL and IL) hemispheres using a
complex motor fMRI task with variable grip force
performed with dominant and non-dominant hands (DH and
NDH) in right handed healthy subjects. We showed there
are: 1) increased activations in more areas at the
highest force when performing the task using the NDH. 2)
More activations in the right hemisphere irrespective of
the hand or force level. 3) Common areas in CL and IL
hemispheres at specific force levels such as SMA. 4)
Consistent bilateral cerebellum involvement when
performing the task using NDH
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