Development of a Clinical Protocol for Magnetic Resonance Elastography of Brain

Manual palpation plays an important role in the clinician's routine. This is unfeasible when the tissue of interest is inaccessible, such as the brain inside the skull. Magnetic resonance elastography (MRE) has the potential to replace palpation, by objectively assessing the mechanical properties of tissue. However, for the implementation of this technique in clinical practice there is an abundance of issues that need to be addressed. The aim of this study is the development of a clinical protocol suitable for the human brain, looking at the choice of actuator, MR sequence, wave frequency and RF coil.

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