Abstract #1766
In-vivo 3D Magnetic Resonance Volumetric Analysis of Fetal Cerebellum: From normal to pathology (unilateral cerebellar hypoplasia)
Martina Gianoni 1,2 , Marie Schaer 3 , Sbastien Tourbier 1,2 , Yvan Vial 4 , Maud Cagneaux 5 , Patric Hagmann 1 , Reto Meuli 1 , Laurent Guibaud 5 , and Meritxell Bach Cuadra 1,2
1
Radiology Department, University Hospital
Center (CHUV) and University of Lausanne (UNIL),
Lausanne, Vaud, Switzerland,
2
Center
for Biomedical Imaging (CIBM), Lausanne, Vaud,
Switzerland,
3
University
of Geneva, Switzerland,
4
Department
de Gyncologie-obsttrique, University Hospital Center
(CHUV) and University of Lausanne (UNIL), Vaud,
Switzerland,
5
Radiology
Department, Hpital Femme, Mre et Enfant, Lyon, France
MRI is increasingly being used for the fetal central
nervous system studies in vivo. Fast MR acquisition
schemes in combination with advanced image processing
reconstruction methods allow the quantitative studies of
cerebellar volume of the fetus in-utero based on high
resolution MRI. In this study we estimated the
cerebellar volume of 9 healthy subjects coming from
different sites. Their volumes match the previously
reported results. We also study one case with unilateral
cerebellar hypoplasia, showing that the pathological
hemisphere is an outlier of the healthy hemispheric
volumes regression over the gestational age.
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