Abstract #1726
MRI Acquisition and Analysis Protocol for In Vivo Grey Matter and White Matter Cross-Sectional Area Measurements in the Lumbo-Sacral Enlargement at 3T
Marios C. Yiannakas 1 , Puneet Kakar 1 , Luke R. Hoy 1 , David H. Miller 1 , and Claudia A. M. Wheeler-Kingshott 1
1
Neuroinflammation, UCL - Institute of
Neurology, London, London, United Kingdom
A new image acquisition and analysis protocol is
presented allowing segmentation of grey matter (GM) and
white matter (WM) within the lumbo-sacral enlargement
(LSE) at 3T. The optimised image acquisition scheme in
conjunction with a robust image analysis method
represents a clinically-viable method for obtaining
reproducible measurements of GM and WM cross-sectional
areas (CSA) within the LSE. In this work, normative
tissue-specific CSA data are presented, hitherto
unreported; future studies will investigate the value of
the method presented here for assessing neurological
diseases.
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