Abstract #1178
Rapid increase of marrow fat content and decrease of marrow perfusion in females underwent bilateral oophorectomy: An magnetic resonance based longitudinal study of lumbar vertebra
Yi-Xiang Wang 1 , David KW Yeung 1 , Min Deng 1 , Jing Yuan 1 , and James F Griffith 1
1
Dept Imaging and Interventional Radiology,
The Chinese University of Hong Kong, Shatin, NT, Hong
Kong
Lumbar spine bone mineral density (BMD) with
quantitative CT, marrow fat fraction (FF) and marrow
perfusion using MRS and DCE MRI at the L3 vertebra in 6
females underwent hysterectomy and bilateral
salpingo-oophorectomy were performed. Reduced BMD,
increased marrow FF, and reduced marrow perfusion
occurred in synchrony. There was a sharp decrease of
12.57.2% for BMD (n=6), a sharp increase of 92.246.3%
(n=6) for FF, a sharp decrease of 23.63.9% for maximum
enhancement (n=5), and of 45.47.7% for enhancement
slope (n=5) during the initial 3 months post surgery.
These changes occurred at a slower rate during the later
follow-up period.
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