Abstract #0717
Whole Brain Perfusion Using Dynamic pCASL with Multiband Look-locker EPI
Ke Zhang 1 , Seong Dae Yun 1 , and N. Jon Shah 1,2
1
Institute of Neuroscience and Medicine 4,
Forschungszentrum Jlich GmbH, Jlich, Germany,
2
Faculty
of Medicine, Department of Neurology, JARA, RWTH Aachen
University, Aachen, Germany
To quantitatively measure CBF with ASL, multiple readout
with different post-labeling delay is preferred incase
of various blood arrival time. One approach for sampling
the tracer kinetics curve with increasing post-labeling
delays is using Look-Locker imaging. Due to the signal
recovery of the labeled blood, the slice number in the
readout is limited. In this study, multiband excitation
technique was applied in Look-locker readout to triple
the readout slices for the dynamic pCASL. Preliminary
results show that the quantitative CBF can be acquired
with whole brain coverage using multiband technique in
the same measurement time as using singleband
excitation.
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