Abstract #0670
Robust 2D Diffusion Weighted Chemical Shift Imaging (DW-CSI) of the human brain at 7T
Ece Ercan 1 , Aranee Techawiboonwong 2 , Maarten J. Versluis 1 , Andrew G. Webb 1 , and Itamar Ronen 1
1
C.J. Gorter Center for High Field MRI,
Department of Radiology, Leiden University Medical
Center, Leiden, Netherlands,
2
Electrical
Engineering, Mahidol University, Nakornpathom, Thailand
2D Diffusion Weighted Chemical Shift (DW-CSI) Imaging is
a challenging method which lacks robustness due to the
multi-shot nature of the acquisition, combined with the
low SNR and the relatively high gradient strength needed
for adequate diffusion weighting of the slow diffusing
metabolites. Here, we show for the first time a method
that accounts for both amplitude and phase inter-shot
fluctuations, and generates robust, reproducible and
anatomically meaningful DW-CSI and metabolite ADC maps.
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