Abstract #0666
Rotating Short-Axis EPI blades as veering diffusion gradient directions with composite reconstruction (RSA)
Yu-Chien Wu 1,2 and Chandana Kodiweera 1
1
Dartmouth College, Hanover, New Hampshire,
United States,
2
Radiology
and Imaging Sciences, Indiana University, Indianapolis,
Indiana, United States
We propose a novel sequence, RSA, for fast and high
spatial resolution advanced Diffusion-Weighted Imaging (DWI),
which has been used widely to assess the integrity and
directional information of white matter. Conventionally,
DWI uses single-shot spin-echo EPI sequences. However,
SS-EPI suffers from geometric distortion and long echo
time (TE) with high spatial resolution (e.g, cubic voxel
size of 1mm). Moreover, approaches using high and/or
multiple b-values demand adequate SNR for accurate
estimations. Because only one short-axis blade is
acquired per DW direction in the RSA sequence, it
reduces geometric distortion, shortens TE to increase
signals, and reduces the scan time.
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