Abstract #0514
Hemodynamic Evaluation of Cerebral Arteriovenous Malformations with Combined 4D Flow and Perfusion MRI
Can Wu 1 , Timothy Carroll 1,2 , Sameer Ansari 2,3 , Amir Honarmand 2,3 , Parmede Vakil 2 , Michael Hurley 2,3 , Bernard Bendok 2,3 , James Carr 2 , and Michael Markl 1,2
1
Biomedical Engineering, Northwestern
University, Chicago, IL, United States,
2
Radiology,
Northwestern University, Chicago, IL, United States,
3
Neurological
Surgery, Northwestern University, Chicago, IL, United
States
4D flow and perfusion MRI were combined to
quantitatively evaluate macro- and microvascular
hemodynamics in cerebral arteriovenous malformations
(AVMs), investigate the influence of Spetzler-Martin
grade on AVM hemodynamics, and identify potential
relationships between changes in macro- and
microvascular flow and perfusion. The results
demonstrated the influence of Spetzler-Martin grade on
AVM hemodynamics in the feeding arteries, draining
veins, and the straight sinus. In addition, we could
identify significant relationships between large vessel
flow and perfusion ratios. These findings demonstrate
the potential of our imaging protocol for the
comprehensive characterization of the impact of AVMs on
macro- and microvascular hemodynamics.
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