Abstract #0500
Flow Characteristics in Bicuspid Aortic Valve Relatives compared to normal controls using 4D flow MRI
Susanne Schnell 1 , Alex J Barker 1 , Pegah Entezari 1 , A Reza Hornamand 1 , Pim van Ooij 1 , S Chris Malaisrie 2 , Patrick M McCarthy 2 , Jeremy Collins 1 , James C Carr 1 , and Michael Markl 1,3
1
Radiology, Northwestern University, Chicago,
Illinois, United States,
2
Surgery,
Cardiac Surgery Division, Northwestern University,
Chicago, Illinois, United States,
3
Biomedical
Engineering, Northwestern University, Evanston,
Illinois, United States
We evaluated flow dynamics, aorta diameter and geometry
in relatives with a family member expressing a bicuspid
aortic valve (BAV) and compared results to normal
volunteers using contrast enhanced cardiac MRI and 4D
flow MRI. The findings demonstrate subtle but
significant differences in aortic hemodynamics in BAV
relatives compared to age-matched normal controls. Of
note, BAV relatives expressed more cubic shaped aortas,
which may explain the observed differences. In fact, the
significant higher vortex flow in the BAV relatives in
the ascending and descending, as well as the
significantly lower WSS was related to cubic aortic
shape.
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