Abstract #0489
Functional connectivity of the primary olfactory cortex is decreased in Alzheimers disease and mild cognitive impairment
Megha M Vasavada 1 , Han Zhang 2 , Jianli Wang 1 , Prasanna Karunanayaka 1 , Paul Eslinger 3 , David Gill 4 , Bing Zhang 5 , and Qing X Yang 1
1
Radiology, Pennsylvania State College of
Medicine, Hershey, PA, United States,
2
Hangzhou
Normal University, Hangzhou, Zhejiang, China,
3
Neurology,
Pennsylvania State College of Medicine, PA, United
States,
4
Unity
Rehabilitation and Neurology at Ridgeway, NY, United
States,
5
Radiology,
Nanjing university medical school, Nanjing, China
Olfactory deficits are known to occur in patients with
mild cognitive impairment (MCI) and early Alzheimers
disease. In this work, we performed olfactory functional
magnetic resonance imaging of the primary olfactory
cortex and demonstrated that the primary olfactory
cortex is involved functionally in early Alzheimers
disease.
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