Abstract #0448
High resolution mechanical imaging of the human kidney
Jing Guo 1 , Kaspar-Josche Streitberger 1 , Heiko Tzschaetzsch 1 , Sebastian Hirsch 1 , Juergen Braun 2 , and Ingolf Sack 1
1
Department of Radiology, Charite -
Universitaetsmedizin Berlin, Berlin, Berlin, Germany,
2
Department
of Medical Informatics, Charite - Universitaetsmedizin
Berlin, Berlin, Germany
Renal fibrosis can be detected by MR elastography (MRE)
based on altered mechanical tissue properties. However,
MRE has been limited in providing high resolution
mechanical parameter maps of the kidney due to
low-resolution shear wave images and ill-posed solutions
of the inverse problem of MRE. We here overcome both
problems by an optimized single shot MRE sequence and
multifrequency dual elasto visco inversion. As a result,
high resolution MRE maps are obtained which for the
first time enable radiologists to analyze the regional
variation of the kidney's viscoelastic properties on a
pixel-to-pixel base.
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