Abstract #0390
Functional MRI reveals the reliable brain modulation effect induced by focused ultrasound
HSIN-YI LAI 1,2 , PO-CHUN CHU 3 , HSIANG-WEI HU 4 , YOU-YIN CHEN 5 , YEN-YU IAN SHIH 6 , and YU-CHENG PEI 1,2
1
School of Medicine, Chang Gung University,
Taoyuan, Taiwan,
2
Department
of Physical Medicine and Rehabilitation, Chang-Gung
Memorial Hospital, Taoyuan, Taiwan,
3
Electrical
Engineering, Chang Gung University, Taoyuan, Taiwan,
4
Department
of Biomedical Engineering, National Yang-Ming
University, Taipei, Taiwan,
5
National
Yang-Ming University, Taipei, Taiwan,
6
Department
of Neurology, Biomedical Research Imaging Center,
University of North Carolina, Chapel Hill, NORTH
CAROLINA, United States
This study demonstrates focused ultrasound
co-administrated with microbubbles can modulate local
brain activities. Focused ultrasound with acoustic
pressures of 0.3 MPa produced reliable and reversible
brain modulation. This present study proposed a novel
non-invasive, reversible and localized brain modulated
method which is suitable for a variety of
neurophysiological experiments and clinical
applications.
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