Abstract #0235
Non-Contrast Myocardial Fibrosis Imaging using MT-weighted Balanced Steady State Free Precession MRI
Steve W Leung 1 , Richard Lawless 1 , Vincent L Sorrell 1 , and Moriel Vandsburger 1
1
University of Kentucky, Lexington, Kentucky,
United States
The development of myocardial fibrosis significantly
heightens the risk of sudden cardiac death. Late
gadolinium enhanced (LGE) MRI has become the reference
standard for detection of fibrotic tissue, however,
multiple high risk patient cohorts are contraindicated
to LGE-CMR. We developed a novel fibrosis imaging
technique that utilizes magnetization transfer (MT) from
fibrotic tissue for completely non-invasive diagnosis of
fibrotic remodeling. In this preliminary study,
demonstrate excellent correlation of fibrosis as
identified with MT-weighted bSSFP MRI with LGE-CMR and
measurement of gadolinium partition coefficient.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
