Abstract #0229
Conduct disorder and callous unemotional traits are related to the microstructure of the dorsal default-mode network
Arjun Sethi 1 , Quinton Deeley 1 , Sagari Sarkar 1 , Marco Catani 1 , Flavio Dell'Acqua 1 , Declan DGM Murphy 1 , and Michael C Craig 1
1
Institute of Psychiatry, King's College
London, London, England, United Kingdom
This work supports the importance of the white matter
underpinning a mediodorsal component of the default-mode
network (the dorsal cingulum) in conduct disorder and
callous unemotional traits. Diffusion MRI tractography
shows that decreased radial diffusivity in this tract
portion is reduced in adolescents with conduct disorder,
and that radial diffusivity is negatively correlated
with callous-unemotional traits in the whole sample.
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