Abstract #0210
Quantitative magnetization transfer imaging of rodent glioma using selective inversion recovery
Junzhong Xu 1 , Ke Li 1 , Zhongliang Zu 1 , Xia Li 1 , Dainel F Gochberg 1 , and John C Gore 1
1
Institute of Imaging Science, Vanderbilt
University, Nashville, Tennessee, United States
This study demonstrates the first implementation of
quantitative MT imaging of cancer using selective
inversion recovery. In addition, a new SIR-EPI sequence
was developed to accelerate the acquisition but retain
the fitting accuracy of qMT parameters. The results
presented not only assist better understanding of the
changes in the macromolecular contents of tumors, but
also are important for quantifying other imaging
contrasts such as chemical exchange saturation transfer
(CEST) of tumors.
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