Abstract #0121
Quantitative properties (water content, relaxometry, MT) of the post mortem brain: a baseline for normal tissue
Ana-Maria Oros-Peusquens 1 and N. Jon Shah 1,2
1
INM-4, Research Centre Jlich, Jlich,
Germany,
2
Department
of Neurology, RWTH Aachen University, Aachen, Germany
MRI of fixed tissue is increasingly used to investigate
the brain. However, properties of tissue change with
fixation. This study investigates post mortem
formalin-fixed brains quantitatively in order to provide
a baseline for MR parameters characteristic of healthy
brain tissue. The variability of several quantitative
MRI parameters is characterized in fixed brain tissue
obtained from donors unaffected by neurological
conditions. Among other parameters, quantitative water
content determined non-invasively with MRI is reported
on whole human post mortem brains for the first time to
our knowledge. Correlations between different parameters
were investigated and compared to the same quantities
measured in vivo.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
